Bariatric Surgery Effective, Cost-Effective in Obese With NASH

Share this content:
Bariatric Surgery Effective, Cost-Effective in Obese With NASH
Bariatric Surgery Effective, Cost-Effective in Obese With NASH

WEDNESDAY, Dec. 7, 2016 (HealthDay News) -- For patients with nonalcoholic steatohepatitis (NASH), bariatric surgery is effective and cost-effective for obese patients, while for overweight patients, cost-effectiveness is limited to those with F3 fibrosis, according to a study published online Nov. 23 in Hepatology.

Matthew J. Klebanoff, from Massachusetts General Hospital in Boston, and colleagues examined the effectiveness and cost-effectiveness of surgery to manage NASH using a state-transition model. The benefits and harms of laparoscopic Roux-en-Y gastric bypass surgery were simulated for patients defined by weight class and fibrosis stage (F0 to F3).

The researchers found that in obese patients, surgery and intensive lifestyle intervention (ILI) increased quality-adjusted life-years (QALYs) by 0.678 to 2.152 and by 0.452 to 0.618, respectively, relative to no treatment. In patients with F0 to F3 fibrosis, the incremental cost-effectiveness ratios (ICERs) were $48,836, $24,949, and $19,222 per QALY for mild, moderate, or severe obesity, respectively. Surgery increased QALYs by 0.050 to 0.824 in overweight patients with F0 to F3, and ILI increased QALYs by 0.031 to 0.164. It was cost-effective to reserve treatment only for F3 patients among overweight patients, with ICERS of $30,484 and $25,367 per QALY for providing surgery or ILI, respectively, only to F3 patients.

"Our results highlight the promise of bariatric surgery for treating NASH and underscore the need for clinical trials in this area," the authors write.

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ATS: Cancer-Related Suicide Risk Highest for Lung Cancer Patients

ATS: Cancer-Related Suicide Risk Highest for Lung Cancer ...

Odds up four-fold compared to people in the general population

Mortality Rates Found Lower at Major Teaching Hospitals

Mortality Rates Found Lower at Major Teaching Hospitals

Researchers assessed 30-day survival for older patients

Opioid Use Before TKA May Lead to Worse Pain After Surgery

Opioid Use Before TKA May Lead to Worse ...

Researchers suggest limiting opioid prescriptions might optimize benefits of TKA

is free, fast, and customized just for you!

Already a member?

Sign In Now »