Ketamine Beneficial for Certain Patients With Mood Disorders

Share this content:
Ketamine Beneficial for Certain Patients With Mood Disorders
Ketamine Beneficial for Certain Patients With Mood Disorders

WEDNESDAY, March 8, 2017 (HealthDay News) -- Use of ketamine for treatment of mood disorders should include appropriate patient selection and consideration of potential risks of treatment, according to a consensus statement published online March 1 in JAMA Psychiatry.

Gerard Sanacora, M.D., Ph.D., from the Yale University School of Medicine in New Haven, Conn., and colleagues examined data on the use of ketamine for mood disorder treatment.

The researchers note that ketamine may be helpful for some patients with mood disorders. Appropriate patient section should include diagnostic considerations, with the strongest evidence supporting ketamine's benefit in treatment of major depressive disorder without psychotic features, as well as assessment of other medical, psychological, and social factors. Most studies supporting ketamine's benefit assessed efficacy during the first week following a single infusion; emerging studies indicate that repeated dosing may extend the efficacy for at least several weeks. However, the available data are limited and potential risks associated with ketamine should be considered before its use.

"The suggestions provided are intended to facilitate clinical decision making and encourage an evidence-based approach to using ketamine in the treatment of psychiatric disorders considering the limited information that is currently available," the authors write. "This article provides information on potentially important issues related to the off-label treatment approach that should be considered to help ensure patient safety."

Several authors disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Seeks to Increase Number of Generic Drugs on Market

FDA Seeks to Increase Number of Generic Drugs ...

Agency will now give priority reviews to new generic drugs until there are at least three available

PPIs Not Found to Raise Risk of Alzheimer's Disease

PPIs Not Found to Raise Risk of Alzheimer's ...

New research debunks other studies suggesting that PPIs cause mental decline

Aspirin Effective in Pregnancies at High Risk for Preeclampsia

Aspirin Effective in Pregnancies at High Risk for ...

Odds of preeclampsia drop for high-risk women who take 150 mg of aspirin daily, researchers find

is free, fast, and customized just for you!

Already a member?

Sign In Now »