Overall Vagotomy Not Linked to Risk of Parkinson's Disease

This article originally appeared here.
Share this content:
Overall Vagotomy Not Linked to Risk of Parkinson's Disease
Overall Vagotomy Not Linked to Risk of Parkinson's Disease

THURSDAY, April 27, 2017 (HealthDay News) -- Overall vagotomy is not associated with the risk of Parkinson's disease (PD), according to a study published online April 26 in Neurology.

Bojing Liu, from the Karolinska Institutet in Sweden, and colleagues conducted a matched-cohort study of 9,430 vagotomized patients (3,445 truncal and 5,978 selective) identified between 1970 and 2010 and 377,200 reference individuals matched by sex and year of birth in a 40-to-1 ratio. They followed participants from the date of vagotomy until PD diagnosis, death, or emigration or until Dec. 31, 2010.

During 7.3 million person-years of follow-up, the researchers identified 4,930 cases of incident PD. The incidence of PD was 61.8 and 67.5 per 100,000 person-years among vagotomized patients and reference individuals, respectively. Overall, there was no correlation for vagotomy with the risk of PD (hazard ratio, 0.96; 95 percent confidence interval, 0.78 to 1.17). Patients with truncal vagotomy had a trend toward lower risk (hazard ratio, 0.78; 95 percent confidence interval, 0.55 to 1.09), which may have been driven by truncal vagotomy at least five years before diagnosis (hazard ratio, 0.59; 95 percent confidence interval, 0.37 to 0.93). There was no correlation between selective vagotomy and the risk of PD.

"Although overall vagotomy was not associated [with] the risk of PD, we found suggestive evidence for a potential protective effect of truncal, but not selective, vagotomy against PD development," the authors write.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

SAMHSA: Youth Binge Drinking Rates Down in the United States

SAMHSA: Youth Binge Drinking Rates Down in the ...

But one in seven still consumed excess alcohol at least once in past month, study finds

Carpal Tunnel Up With Increased Electronic Device Use

Carpal Tunnel Up With Increased Electronic Device Use

Especially for those who spend more than five hours a day on their devices, researchers say

Guided Approach to Exercise May Help Chronic Fatigue Patients

Guided Approach to Exercise May Help Chronic Fatigue ...

Guided self-help approach to graded exercise program safe, reduces fatigue

is free, fast, and customized just for you!

Already a member?

Sign In Now »