Noninvasive Imaging Deemed Adequate in Prediction of MACE

This article originally appeared here.
Share this content:
Noninvasive Imaging Deemed Adequate in Prediction of MACE
Noninvasive Imaging Deemed Adequate in Prediction of MACE

WEDNESDAY, March 15, 2017 (HealthDay News) -- Computed tomography (CT) angiography and CT myocardial stress perfusion imaging have similar prediction of two-year major adverse cardiovascular events (MACE) as combined invasive coronary angiography (ICA) and stress single photon emission CT myocardial perfusion imaging, according to a study published online March 14 in Radiology.

Marcus Y. Chen, M.D., from the U.S. National Institutes of Health in Bethesda, Md., and colleagues compared the prognostic importance of combined CT angiography and CT myocardial stress perfusion imaging with combined ICA and stress single photon emission CT myocardial perfusion imaging for 381 patients clinically referred for ICA.

The researchers found that 51 of 379 patients (13.5 percent) had a MACE. The two-year MACE-free rates were 94 percent negative for coronary artery disease (CAD) versus 82 percent positive for CAD for combined CT angiography and CT perfusion findings. These values were similar to combined ICA and single photon emission CT findings of 93 percent negative for CAD versus 77 percent positive for CAD (both P < 0.001). For the identification of MACE at two-year follow-up, the area under the receiver operating characteristic curve was similar for combined CT angiography and CT perfusion and for combined ICA and single photon emission CT (68 and 71, respectively; P = 0.36).

"Combined CT angiography and CT perfusion enables similar prediction of two-year MACE, late MACE, and event-free survival similar to that enabled by ICA and single photon emission CT," the authors write. "A purely noninvasive anatomic and physiologic assessment via CT angiography and myocardial perfusion is adequate to identify patients with a MACE at two-year follow-up in symptomatic patients suspected of having CAD."

Several authors disclosed financial ties to medical device companies, including Toshiba Medical Systems.

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Seeks to Increase Number of Generic Drugs on Market

FDA Seeks to Increase Number of Generic Drugs ...

Agency will now give priority reviews to new generic drugs until there are at least three available

PPIs Not Found to Raise Risk of Alzheimer's Disease

PPIs Not Found to Raise Risk of Alzheimer's ...

New research debunks other studies suggesting that PPIs cause mental decline

Aspirin Effective in Pregnancies at High Risk for Preeclampsia

Aspirin Effective in Pregnancies at High Risk for ...

Odds of preeclampsia drop for high-risk women who take 150 mg of aspirin daily, researchers find

is free, fast, and customized just for you!

Already a member?

Sign In Now »