Antioxidant, Carotene Intake Tied to Increased Function in ALS

Share this content:
Antioxidant, Carotene Intake Tied to Increased Function in ALS
Antioxidant, Carotene Intake Tied to Increased Function in ALS

WEDNESDAY, Oct. 26, 2016 (HealthDay News) -- Antioxidants, carotenes, and fruit and vegetable intake is associated with higher amyotrophic lateral sclerosis (ALS) function, according to research published online Oct. 24 in JAMA Neurology.

Jeri W. Nieves, Ph.D., from the Mailman School of Public Health at Columbia University in New York City, and colleagues examined the correlations between nutrients and ALS function and respiratory function at diagnosis. They conducted a cross-sectional baseline analysis of the ALS Multicenter Cohort Study of Oxidative Stress at 16 U.S. ALS clinics among 302 patients with ALS symptom duration of 18 months or less.

The researchers found that higher intakes of antioxidants and carotenes from vegetables correlated with higher ALS Functional Rating Scale-Revised (ALSFRS-R) scores or percentage predicted forced vital capacity (FVC) in regression analysis of nutrients. There were positive associations for empirically weighted indices using the weighted quantile sum regression method of "good" micronutrients and "good" food groups with ALSFRS-R scores and percentage FVC (all P < 0.001). In exploratory analyses, positive and significant associations were seen for selected vitamins with ALSFRS-R scores and percentage FVC.

"Those responsible for nutritional care of the patient with ALS should consider promoting fruit and vegetable intake since they are high in antioxidants and carotenes," the author write.

Several authors disclosed financial ties to the biopharmaceutical industry.

Full Text
Editorial (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Hospitals Vary Widely in Moving Stroke Patients to Comfort Care

Hospitals Vary Widely in Moving Stroke Patients to ...

Doctors more apt to suggest it sooner for older, white, female, and uninsured patients

Peri-Op IV Acetaminophen May Reduce Post-Op Pain in Sinus Sx

Peri-Op IV Acetaminophen May Reduce Post-Op Pain in ...

Reduction in immediate postoperative pain after endoscopic sinus surgery, but results inconclusive

Location of Body Fat Can Indicate Obesity-Related Cancer Risk

Location of Body Fat Can Indicate Obesity-Related Cancer ...

Where fat is carried is as strong a predictor as BMI, researchers suggest

is free, fast, and customized just for you!

Already a member?

Sign In Now »