Renal Outcomes Up With BP <120/70 in T1DM

Share this content:
Renal Outcomes Up With BP &#60;120/70 in T1DM
Renal Outcomes Up With BP <120/70 in T1DM

TUESDAY, Nov. 29, 2016 (HealthDay News) -- For patients with type 1 diabetes, blood pressure (BP) of <120/70 mm Hg is associated with a substantially reduced risk of adverse renal outcomes, according to a study published online Nov. 21 in Diabetes Care.

Elaine Ku, M.D., from the University of California in San Francisco, and colleagues compared BP levels and their association with the risk of renal outcomes among 1,441 participants with type 1 diabetes aged 13 to 39 years who had been randomized to receive intensive versus conventional glycemic control. Time-updated systolic BP (SBP) and diastolic BP (DBP) were the exposures of interest.

The researchers identified 84 cases of stage III chronic kidney disease (CKD) and 169 cases of macroalbuminuria during a median follow-up of 24 years. Compared with SBPs between 130 and 140 mm Hg, SBP in the <120 mm Hg range correlated with a 0.59 times risk of macroalbuminuria and a 0.32 times risk of stage III CKD, in adjusted models. Compared with DBPs between 80 and 90 mm Hg, DBP in the <70 mm Hg range correlated with a 0.73 times risk of macroalbuminuria and a 0.47 times risk of stage III CKD. There was no interaction between BP and glycemic control strategy.

"A lower BP (<120/70 mm Hg) was associated with a substantially lower risk of adverse renal outcomes, regardless of the prior assigned glycemic control strategy," the authors write.

Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

SAMHSA: Youth Binge Drinking Rates Down in the United States

SAMHSA: Youth Binge Drinking Rates Down in the ...

But one in seven still consumed excess alcohol at least once in past month, study finds

Carpal Tunnel Up With Increased Electronic Device Use

Carpal Tunnel Up With Increased Electronic Device Use

Especially for those who spend more than five hours a day on their devices, researchers say

Guided Approach to Exercise May Help Chronic Fatigue Patients

Guided Approach to Exercise May Help Chronic Fatigue ...

Guided self-help approach to graded exercise program safe, reduces fatigue

is free, fast, and customized just for you!

Already a member?

Sign In Now »