Initiation, Adherence to AIs Low for Older Women With DCIS

Share this content:
Initiation, Adherence to AIs Low for Older Women With DCIS
Initiation, Adherence to AIs Low for Older Women With DCIS

MONDAY, Oct. 31, 2016 (HealthDay News) -- For older women with estrogen receptor (ER)-positive ductal carcinoma in situ (DCIS), initiation of aromatase inhibitors (AIs) and adherence to treatment are low, according to a study published online Oct. 25 in Cancer.

Hui Zhao, Ph.D., from the University of Texas MD Anderson Cancer Center in Houston, and colleagues examined the initiation and five-year adherence levels for women aged 66 to 85 years who had been diagnosed with ER-positive DCIS between 2007 and 2011. Data were reviewed for 2,871 women.

The researchers found that about 45 percent of the women initiated treatment with tamoxifen or AIs within one year of diagnosis. Hormone therapy was more likely to be initiated among women aged 66 to 70 years who underwent lumpectomy and radiation therapy. Patients' geographic locations, education, marital status, year of diagnosis, and race/ethnicity also correlated with initiation of therapy. Among users there was a decrease in adherence from 67 percent in the first year to 30 percent in the fifth year.

"Initiation and adherence levels for tamoxifen or AIs among older women with ER-positive DCIS are low," the authors write. "Future studies should develop methods to ensure that informed discussions take place between health care providers and patients regarding hormonal therapy for cancer prevention."

Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

FDA Seeks to Increase Number of Generic Drugs on Market

FDA Seeks to Increase Number of Generic Drugs ...

Agency will now give priority reviews to new generic drugs until there are at least three available

PPIs Not Found to Raise Risk of Alzheimer's Disease

PPIs Not Found to Raise Risk of Alzheimer's ...

New research debunks other studies suggesting that PPIs cause mental decline

Aspirin Effective in Pregnancies at High Risk for Preeclampsia

Aspirin Effective in Pregnancies at High Risk for ...

Odds of preeclampsia drop for high-risk women who take 150 mg of aspirin daily, researchers find

is free, fast, and customized just for you!

Already a member?

Sign In Now »