New Findings Offer Hope for Those With Severe Hemophilia

Share this content:
New Findings Offer Hope for Those With Severe Hemophilia
New Findings Offer Hope for Those With Severe Hemophilia

THURSDAY, May 26, 2016 (HealthDay News) -- Two new studies could pave the way to major changes in how severe cases of hemophilia are treated. Both studies were published in the May 26 issue of the New England Journal of Medicine.

In one study, an international team of researchers randomly assigned 264 young children newly diagnosed with severe hemophilia to start replacement therapy with either blood-derived or recombinant factor VIII.

Overall, 37 percent of children on the recombinant therapy developed antibodies. That compared with 23 percent of children on blood-based therapy. Lead researcher Flora Peyvandi, M.D., of the University of Milan, said the findings suggest blood-derived factor VIII is the "better choice" for children beginning therapy. The findings do not apply to patients who've been on therapy for a while, Peyvandi told HealthDay.

The second study tested emicizumab in 18 patients with severe hemophilia. Over three months, 72 percent had no bleeding episodes, and it was just as effective in patients who'd developed antibodies to factor VIII as those who were antibody-free.

The second study was funded by Chugai Pharmaceutical, one of the companies developing emicizumab.

Abstract 1
Full Text (subscription or payment may be required)
Abstract 2
Full Text
Editorial

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Progress Made on Genetic Test for Anal Cancer

Progress Made on Genetic Test for Anal Cancer

But research is still in early stages

Four Separate Events Led to Zika's Introduction Into Florida

Four Separate Events Led to Zika's Introduction Into ...

Virus strains came from the Caribbean and Latin America, researchers say

New Health Care Act Could Result in 23 Million Losing Insurance

New Health Care Act Could Result in 23 ...

While premiums may lower over the long-term, many would face much higher out-of-pocket costs

is free, fast, and customized just for you!

Already a member?

Sign In Now »