ENDO: Corticosteroids Linked to Increased Risk of MetS

This article originally appeared here.
Share this content:
ENDO: Corticosteroids Linked to Increased Risk of MetS
ENDO: Corticosteroids Linked to Increased Risk of MetS

WEDNESDAY, April 5, 2017 (HealthDay News) -- Use of corticosteroids (CS) is associated with increased odds of metabolic syndrome (MetS) and elevated body mass index (BMI), according to a study presented at the annual meeting of The Endocrine Society, held from April 1 to 4 in Orlando, Fla.

Mesut Savas, M.D., from Erasmus MC in Rotterdam, Netherlands, and colleagues evaluated the correlation between CS use and MetS and BMI in 140,879 participants from the Lifelines cohort study.

The researchers found that 10.9 percent of the study population was currently using CS. Compared with nonusers, CS users had higher odds of having MetS (odds ratio [OR], 1.11; 95 percent confidence interval [CI], 1.06 to 1.18; P < 0.001) and increased body mass index (+0.31 kg/m²; 95 percent CI, 0.24 to 0.39; P < 0.001). Markedly stronger associations were seen in women (MetS: OR, 1.21 [95 percent CI, 1.12 to 1.31]; BMI: OR, +0.43 [95 percent CI, 0.32 to 0.54) versus men (MetS: OR, 0.98 [95 percent CI, 0.90 to 1.06]; BMI: OR, +0.04 [95 percent CI, −0.07 to 0.14]). The odds of MetS were increased for users of systemic (OR, 1.24 [95 percent CI, 1.01 to 1.53]) and only local (OR, 1.11 [95 percent CI, 1.05 to 1.17]) administration forms.

"We need studies that will follow corticosteroid users and nonusers over time and monitor for development of the metabolic syndrome," Savas said in a statement.

Abstract
More Information

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Hospitals Vary Widely in Moving Stroke Patients to Comfort Care

Hospitals Vary Widely in Moving Stroke Patients to ...

Doctors more apt to suggest it sooner for older, white, female, and uninsured patients

Peri-Op IV Acetaminophen May Reduce Post-Op Pain in Sinus Sx

Peri-Op IV Acetaminophen May Reduce Post-Op Pain in ...

Reduction in immediate postoperative pain after endoscopic sinus surgery, but results inconclusive

Location of Body Fat Can Indicate Obesity-Related Cancer Risk

Location of Body Fat Can Indicate Obesity-Related Cancer ...

Where fat is carried is as strong a predictor as BMI, researchers suggest

is free, fast, and customized just for you!

Already a member?

Sign In Now »