February 2017 Briefing - Pharmacy

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Here are what the editors at HealthDay consider to be the most important developments in Pharmacy for February 2017. This roundup includes the latest research news from journal articles, as well as the FDA approvals and regulatory changes that are the most likely to affect clinical practice.

Strategies Suggested to Protect Practices From Hackers

TUESDAY, Feb. 28, 2017 (HealthDay News) -- Steps should be taken to protect medical practices, including small practices, from hackers, according to a report published in Medical Economics.

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Diazepam Not Beneficial for Acute Low Back Pain in ER

TUESDAY, Feb. 28, 2017 (HealthDay News) -- There is doubt as to whether diazepam provides benefit in the treatment of low back pain in the emergency department environment, according to a study published online Feb. 7 in the Annals of Emergency Medicine.

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Doctors Need to Discuss Herbal Medication Use With CVD Patients

TUESDAY, Feb. 28, 2017 (HealthDay News) -- While there's little evidence that herbal medications are safe or effective to treat cardiovascular conditions, they remain popular among patients with cardiovascular disease, according to a review published in the March 7 issue of the Journal of the American College of Cardiology.

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Antidepressant Efficacy Varies for Depressive Symptom Clusters

TUESDAY, Feb. 28, 2017 (HealthDay News) -- Antidepressant treatment efficacy varies for empirically-defined clusters of symptoms, according to a study published online Feb. 22 in JAMA Psychiatry.

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Supreme Court Rules Patient Safety Data Subject to Litigation

MONDAY, Feb. 27, 2017 (HealthDay News) -- The Supreme Court of Florida has reversed a District Court of Appeal decision deeming information related to patient safety unprotected from litigation discovery, according to a report published from the American Medical Association.

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Multidrug-Resistant Bacteria Found in Hospital Sinks

MONDAY, Feb. 27, 2017 (HealthDay News) -- Spread of antibiotic-resistant bacteria can occur through sinks and other areas where water can pool inside hospitals, according to a study published online Feb. 24 in Applied and Environmental Microbiology.

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Many Patients Get Opioid Rx While Receiving Buprenorphine

MONDAY, Feb. 27, 2017 (HealthDay News) -- A substantial proportion of patients with opioid use disorder fill prescriptions for non-buprenorphine opioids during and following treatment with buprenorphine, according to a study published online Feb. 23 in Addiction.

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Hormonal Maintenance Tx Ups PFS in Low-Grade Serous Cancer

MONDAY, Feb. 27, 2017 (HealthDay News) -- For women with low-grade serous carcinoma of the ovary or peritoneum, hormonal maintenance therapy (HMT) is associated with improved progression-free survival (PFS), according to a study published online Feb. 21 in the Journal of Clinical Oncology.

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Inhaled Corticosteroids Not Linked to Pneumonia in Children

MONDAY, Feb. 27, 2017 (HealthDay News) -- Inhaled corticosteroids (ICS) do not appear to be associated with the risk of pneumonia in children with asthma, according to a review published online Feb. 24 in Pediatrics.

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CDC: Fatal Drug Overdoses More Than Doubled Since 1999

FRIDAY, Feb. 24, 2017 (HealthDay News) -- Drug overdose deaths have nearly tripled in the United States since 1999, with the largest increases seen for whites and middle-aged Americans, according to a February data brief published by the U.S. Centers for Disease Control and Prevention's National Center for Health Statistics.

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DPP-4i Treatment Doesn't Up MI, Stroke Risk in Seniors

FRIDAY, Feb. 24, 2017 (HealthDay News) -- For older U.S. Medicare beneficiaries, dipeptidyl peptidase-4 inhibitors (DPP-4i) treatment is not associated with increased cardiovascular (CV) risk relative to sulfonylureas (SU) and thiazolidinediones (TZD), according to a study published online Feb. 14 in Diabetes, Obesity and Metabolism.

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Cyberattacks Remain Serious Threat to Health Providers

THURSDAY, Feb. 23, 2017 (HealthDay News) -- Cyberattacks remain a serious threat to small providers as well as big institutions, according to a report published in Medical Economics.

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Stratification Tool IDs Who Will Benefit From Adding Ezetimibe

THURSDAY, Feb. 23, 2017 (HealthDay News) -- For patients stabilized after acute coronary syndrome (ACS), a nine-point risk stratification tool can identify patients who will derive benefit from the addition of ezetimibe to statin therapy, according to a study published in the Feb. 28 issue of the Journal of the American College of Cardiology.

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Glucagon Receptor Antagonist Ups Blood Pressure in T2DM

THURSDAY, Feb. 23, 2017 (HealthDay News) -- For patients with type 2 diabetes, once-daily treatment with the glucagon receptor antagonist LY2409021 is associated with increases in ambulatory blood pressure (BP), according to a study published online Feb. 13 in Diabetes, Obesity and Metabolism.

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Lanadelumab Active in Angioedema With C1 Inhibitor Deficiency

THURSDAY, Feb. 23, 2017 (HealthDay News) -- For patients with hereditary angioedema with C1 inhibitor deficiency, the new kallikrein inhibitor lanadelumab is associated with reduced cleavage of high-molecular-weight kininogen and fewer angioedema attacks, according to a study published in the Feb. 23 issue of the New England Journal of Medicine.

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Off-Label Antidepressant Use Common, but Evidence Lacking

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- Up to one-third of antidepressants are prescribed for pain, insomnia, migraine, or other unapproved uses, but just 16 percent of those off-label prescriptions are supported by strong research, according to a study published online Feb. 21 in The BMJ.

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Health Information Theft a Pressing Concern for U.S. Patients

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- Forty-four percent of U.S. adults are worried about having their personal health care information stolen, according to findings from the Xerox eHealth Survey published Feb. 9 in HIT Consultant.

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Nursing Homes Rarely Use Isolation for Drug-Resistant Bugs

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- Isolation precautions are infrequently used for nursing home (NH) residents with multidrug-resistant organism (MDRO) infection, according to a study published online Feb. 17 in the Journal of the American Geriatrics Society.

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Oral Ciprofloxacin Effective for Treatment of Human Plague

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- Oral ciprofloxacin is effective for the treatment of human plague, caused by Yersinia pestis, according to research published in the March issue of the U.S. Centers for Disease Control and Prevention's Emerging Infectious Diseases.

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Cancer Survivors Likely to Change Rx Drug Use for Financial Reasons

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- Nonelderly cancer survivors are more likely to report changes in prescription drug use for financial reasons than individuals without a cancer history, according to a study published online Feb. 20 in Cancer.

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Weight Loss of 10% Beneficial in Overweight, Not Obese, With DM

WEDNESDAY, Feb. 22, 2017 (HealthDay News) -- For overweight, but not obese, individuals with type 2 diabetes (T2D), sustained weight loss (WL) of 10 percent body weight is associated with clinically meaningful cardiometabolic changes, according to research published online Feb. 19 in Diabetes Care.

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CMS Rule Set to Stabilize Small Health Insurance Markets

TUESDAY, Feb. 21, 2017 (HealthDay News) -- The U.S. Centers for Medicare & Medicaid Services (CMS) has proposed a rule in relation to new reforms intended to stabilize individual and small group health insurance markets for 2018.

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Trials Highlight Benefits, Risks of Testosterone Treatment

TUESDAY, Feb. 21, 2017 (HealthDay News) -- Testosterone treatment can boost bone density and reduce anemia in older men with low levels of the hormone, but it might also increase the risk of future adverse cardiovascular events, a new set of trials suggests. The research was published Feb. 21 in either the Journal of the American Medical Association or JAMA Internal Medicine.

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Patients With Opioid Addiction Benefit From Tx Initiated in ER

TUESDAY, Feb. 21, 2017 (HealthDay News) -- Patients addicted to opioids treated in a hospital emergency department do better when they receive medication to reduce opioid cravings, according to a study published online Feb. 13 in the Journal of General Internal Medicine.

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OD Risk Up in Children Whose Mothers Are Prescribed Opioids

MONDAY, Feb. 20, 2017 (HealthDay News) -- A child's risk of a potentially fatal drug overdose more than doubles if a parent is prescribed an opioid, and appropriate storage guidelines are often not followed, according to research published online Feb. 20 in Pediatrics.

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AAP Urges Doctors Not to Punish Pregnant Women for Opioid Use

MONDAY, Feb. 20, 2017 (HealthDay News) -- Prevention and treatment, not legal action, should be the focus when dealing with pregnant women who use opioids, according to a policy statement from the American Academy of Pediatrics (AAP) published online Feb. 20 in Pediatrics.

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Baricitinib Associated With Significant Improvement in RA

MONDAY, Feb. 20, 2017 (HealthDay News) -- For patients with rheumatoid arthritis who have had an inadequate response to methotrexate, baricitinib is associated with significant clinical improvements, compared to either placebo or adalimumab, according to a study published in the Feb. 16 issue of the New England Journal of Medicine.

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Drug-Induced Lupus Seen With Adalimumab Treatment

MONDAY, Feb. 20, 2017 (HealthDay News) -- In a case report published online Feb. 12 in the Journal of Clinical Pharmacy and Therapeutics, drug-induced lupus erythematosus (DILE) is described in a patient taking adalimumab for psoriasis.

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Increased Active Vitamin D May Help Optimize Muscle Strength

MONDAY, Feb. 20, 2017 (HealthDay News) -- High blood levels of active vitamin D may increase muscle strength, according to a study published online Feb. 15 in PLOS ONE.

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CDC: Influenza Vaccine 48 Percent Effective Overall

FRIDAY, Feb. 17, 2017 (HealthDay News) -- This year's influenza vaccine is a fairly good match for the circulating viruses, according to research published in the Feb. 17 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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Doctors Often Write Rx for Antibiotics If Patients Expect It

FRIDAY, Feb. 17, 2017 (HealthDay News) -- Doctors are more likely to prescribe antibiotics if they think patients expect the medications, according to a study published online Feb. 16 in Health Psychology.

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Metformin Use Linked to Less Vitamin B12 Measurement

FRIDAY, Feb. 17, 2017 (HealthDay News) -- Long-term metformin use is associated with lower serum vitamin B12 concentration, although metformin users are less likely to receive vitamin B12 testing, according to a study published online Feb. 9 in the Journal of the American Geriatrics Society.

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FDA Approves Siliq for Plaque Psoriasis

THURSDAY, Feb. 16, 2017 (HealthDay News) -- The injected drug Siliq (brodalumab) has been approved by the U.S. Food and Drug Administration to treat moderate-to-severe plaque psoriasis in adults.

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Vitamin D May Help Reduce Risk of Acute Respiratory Infection

THURSDAY, Feb. 16, 2017 (HealthDay News) -- There's preliminary evidence that adequate amounts of vitamin D might help lower rates of acute respiratory infections, according to a review published online Feb. 15 in The BMJ.

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Hormone Therapy Doesn't Appear to Protect Against Alzheimer's

THURSDAY, Feb. 16, 2017 (HealthDay News) -- Women who use hormone therapy (HT) after menopause may not have a lower risk of developing Alzheimer's disease (AD), although there is some evidence that long-term use -- over a decade -- might be tied to a lower risk, according to a study published online Feb. 15 in Neurology.

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Health Care Spending Expected to Grow 5.6% Annually to 2025

THURSDAY, Feb. 16, 2017 (HealthDay News) -- Health care spending is expected to grow at an average annual rate of 5.6 percent from 2016 to 2025, according to a report published online Feb. 15 in Health Affairs.

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Doctors' Opioid Rx Patterns Tied to Patient Risk for Long-Term Use

THURSDAY, Feb. 16, 2017 (HealthDay News) -- Emergency department patients are at greater risk for long-term opioid use even after a single prescription from an emergency medicine physician who regularly prescribes them, according to a study published in the Feb. 16 issue of the New England Journal of Medicine.

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Liraglutide May Blunt Impact of Exercise in Dysregulated T2DM

THURSDAY, Feb. 16, 2017 (HealthDay News) -- For individuals with dysregulated type 2 diabetes, the addition of the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide may attenuate the impact of exercise, according to a study published online Feb. 11 in Diabetes, Obesity and Metabolism.

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Review: Cannabidiol May Be Beneficial for Oral Mucositis

THURSDAY, Feb. 16, 2017 (HealthDay News) -- Cannabidiol could be beneficial for the treatment of oral mucositis, although data on its use in dentistry are scarce, according to a review published online Feb. 12 in the Journal of Clinical Pharmacy and Therapeutics.

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Bariatric Surgery Tied to T2DM Resolution in Obese Patients

THURSDAY, Feb. 16, 2017 (HealthDay News) -- Five years after bariatric surgery, patients with type 2 diabetes who have the procedure show better improvements in quality of life and overall health, compared with those who only take diabetes medications, according to a study published in the Feb. 16 issue of the New England Journal of Medicine.

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Bacteria, Fungi Found in Some Medicinal Marijuana Samples

WEDNESDAY, Feb. 15, 2017 (HealthDay News) -- Medical marijuana may carry infectious bacteria and fungi that can pose a life-threatening risk to cancer patients who use it to ease the side effects of chemotherapy, according to a study published online recently in Clinical Microbiology and Infection.

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Similar Adverse Event Risk for Typical, Atypical Antipsychotics

WEDNESDAY, Feb. 15, 2017 (HealthDay News) -- The risks of adverse events are similar with short-term use of typical and atypical antipsychotic medications (APMs) after cardiac surgery in seniors, according to a study published online Feb. 10 in the Journal of the American Geriatrics Society.

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Lixisenatide Beneficial in Seniors With Uncontrolled Diabetes

WEDNESDAY, Feb. 15, 2017 (HealthDay News) -- Lixisenatide is more effective than placebo for older patients with uncontrolled diabetes on their current medication, with no unexpected safety findings, according to a study published online Feb. 10 in Diabetes Care.

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Dulaglutide Linked to Higher Adherence in T2DM

WEDNESDAY, Feb. 15, 2017 (HealthDay News) -- For patients with type 2 diabetes mellitus (T2DM), dulaglutide is associated with higher adherence and lower discontinuation than exenatide once weekly (QW) or liraglutide, according to a study published online Feb. 9 in Diabetes, Obesity and Metabolism.

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No Chemopreventive Effect Seen for H2RAs in Barrett's Esophagus

TUESDAY, Feb. 14, 2017 (HealthDay News) -- For patients with Barrett's esophagus (BE), proton pump inhibitor (PPI) but not histamine-2 receptor antagonist (H2RA) use is associated with reduced risk of neoplastic progression, according to research published online Feb. 11 in the Journal of Digestive Diseases.

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AHA: CVD Expected to Cost U.S. $1.1 Trillion Per Year by 2035

TUESDAY, Feb. 14, 2017 (HealthDay News) -- Cardiovascular disease (CVD) is increasing in the United States, with costs expected to double from $555 billion in 2016 to $1.1 trillion in 2035, a new American Heart Association report estimates.

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Scalp Cooling Device May Help Reduce Chemo-Induced Alopecia

TUESDAY, Feb. 14, 2017 (HealthDay News) -- Scalp cooling devices may reduce chemotherapy-induced alopecia in patients with breast cancer, according to two studies published in the Feb. 14 issue of the Journal of the American Medical Association.

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ACP Issues Guideline for Treating Acute, Subacute, Chronic LBP

TUESDAY, Feb. 14, 2017 (HealthDay News) -- First-line therapy for patients with low back pain should be simple non-pharmacological remedies -- from heat wraps to physical therapy, according to a new clinical practice guideline from the American College of Physicians (ACP) published online Feb. 14 in the Annals of Internal Medicine.

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Cholesterol Lowering Rx Cuts Recurrence in Breast Cancer

TUESDAY, Feb. 14, 2017 (HealthDay News) -- For women with early-stage, hormone receptor-positive invasive breast cancer, initiation of cholesterol-lowering medication (CLM) during endocrine therapy is associated with improved survival and distant recurrence-free intervals, according to research published online Feb. 13 in the Journal of Clinical Oncology.

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NOACs Have Been Widely Adopted Into Practice

TUESDAY, Feb. 14, 2017 (HealthDay News) -- Non-vitamin K antagonist oral anticoagulants (NOACs) have been adopted into practice and are more frequently prescribed than vitamin K antagonists (VKAs) in the Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation trial, according to research published in the Feb. 21 issue of the Journal of the American College of Cardiology.

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AAP Provides Guidance on Anaphylaxis Emergency Plans

MONDAY, Feb. 13, 2017 (HealthDay News) -- All caregivers for children at risk of anaphylaxis should have a written action plan and epinephrine auto-injectors readily available, according to two clinical reports from the American Academy of Pediatrics (AAP) published online Feb. 13 in the Pediatrics.

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Reduced Immune Response After Intradermal Flu Shot in Eczema

MONDAY, Feb. 13, 2017 (HealthDay News) -- For patients with moderate/severe atopic dermatitis (AD), those colonized with Staphylococcus aureus have a reduced immune response to intradermal influenza vaccination, according to a study published online Feb. 13 in the Journal of Allergy and Clinical Immunology.

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Use of Multiple CNS-Affecting Drugs Increasing Among Seniors

MONDAY, Feb. 13, 2017 (HealthDay News) -- There has been a sharp rise in the number of American seniors who take three or more medications that affect their central nervous system, according to a research letter published online Feb. 13 in JAMA Internal Medicine.

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Short-Course Tocilizumab May Up Hep B Reactivation in RA

MONDAY, Feb. 13, 2017 (HealthDay News) -- For patients with rheumatoid arthritis (RA), one to three doses of tocilizumab may increase the risk of hepatitis B virus (HBV) reactivation, according to a study published online Feb. 3 in the International Journal of Rheumatic Diseases.

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Access to Naloxone Eased in Louisiana, Utah

MONDAY, Feb. 13, 2017 (HealthDay News) -- Health officials in Utah and Louisiana have issued orders to make naloxone more widely available in an effort to prevent overdose deaths, according to a report from the American Medical Association.

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Miscarriage Risk in Women With High hsCRP Down With Aspirin

FRIDAY, Feb. 10, 2017 (HealthDay News) -- Daily low-dose aspirin (LDA) may increase the live birth rate for women with high levels of inflammation who previously lost a pregnancy, according to a study published online Feb. 3 in the Journal of Clinical Endocrinology and Metabolism.

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FDA Approves Emflaza for Duchenne Muscular Dystrophy

FRIDAY, Feb. 10, 2017 (HealthDay News) -- Emflaza (deflazacort) has been approved by the U.S. Food and Drug Administration to treat Duchenne muscular dystrophy (DMD) in patients 5 years and older, the agency said Thursday in a news release.

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Rx Adherence Reminders No More Effective at 'Fresh Start' Dates

FRIDAY, Feb. 10, 2017 (HealthDay News) -- Sending medication adherence reminders following fresh-start dates (life and calendar events indicating the start of new cycles) is not effective for increasing medication adherence, according to a research letter published online Feb. 8 in JAMA Cardiology.

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Peroxide Ingestion As 'Cleansing Agent' Can Be Fatal

FRIDAY, Feb. 10, 2017 (HealthDay News) -- Ingesting high-concentration hydrogen peroxide as a "natural cure" or cleansing agent is a dangerous practice that is associated with a high incidence of embolic events, according to a study published recently in Annals of Emergency Medicine.

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Twelve Percent of Women Fill Opioid Rx After Vaginal Delivery

FRIDAY, Feb. 9, 2017 (HealthDay News) -- Twelve percent of women fill an outpatient opioid prescription within five days of vaginal delivery, according to a study published in the March issue of Obstetrics & Gynecology.

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Post-Cesarean Maternal Infection in 8.8 Percent of C-Sections

THURSDAY, Feb. 9, 2017 (HealthDay News) -- For women undergoing cesarean section, 8.8 percent have post-cesarean infection, with pre-incision azithromycin prophylaxis associated with reduced odds of infection, according to research published in the March issue of Obstetrics & Gynecology.

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Shift in Bisphosphonate Tx After 2008 Recommendations

THURSDAY, Feb. 9, 2017 (HealthDay News) -- In response to revised osteoporosis recommendations in 2008, there was a shift in age-related trends in oral bisphosphonate (BP) therapy initiation, according to a study published online Feb. 2 in the Journal of the American Geriatrics Society.

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Intravenous Lidocaine Offers Alternative for ICU Patients' Pain

THURSDAY, Feb. 9, 2017 (HealthDay News) -- Intravenous lidocaine (IVLI) seems safe for reducing pain among patients in the intensive care unit (ICU) with varying degrees of organ dysfunction, according to research published online Feb. 7 in the Journal of Clinical Pharmacology.

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Infection Risk Lower for Etanercept Vs Monoclonal Ab Rx

THURSDAY, Feb. 9, 2017 (HealthDay News) -- For patients with rheumatoid arthritis, etanercept is associated with lower risk for general infections and tuberculosis compared with monoclonal antibody treatment, according to a meta-analysis published online Feb. 3 in the International Journal of Rheumatic Diseases.

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Valproic Acid Plasma Levels Down With Concomitant Meropenem

THURSDAY, Feb. 9, 2017 (HealthDay News) -- Concomitant use of valproic acid (VPA) and meropenem (MEPM) is associated with a decrease in VPA plasma levels, according to a study published online Feb. 1 in the Journal of Clinical Pharmacy and Therapeutics.

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Valsartan Cuts Microalbuminuria in Impaired Glucose Tolerance

THURSDAY, Feb. 9, 2017 (HealthDay News) -- For patients with impaired glucose tolerance (IGT), valsartan is associated with reduced incidence of microalbuminuria, according to a study published online Jan. 17 in Diabetes, Obesity and Metabolism.

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Monophasic HA Filler + Lidocaine Corrects Nasolabial Folds

THURSDAY, Feb. 9, 2017 (HealthDay News) -- The monophasic hyaluronic acid (HA) filler with lidocaine, Dermalax implant plus (PLUS), is not inferior to the biphasic HA Restylane Sub-Q (Sub-Q) for correcting nasolabial folds (NLFs), according to a study published online Feb. 1 in the Journal of Cosmetic Dermatology.

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Novel Oral Glucose Lowering Drugs Cut Risks in T2DM

WEDNESDAY, Feb. 8, 2017 (HealthDay News) -- For patients with type 2 diabetes, novel oral glucose lowering drugs (GLDs) are associated with reduced risks of all-cause mortality, cardiovascular disease (CVD), and hypoglycemia, compared with insulin use, according to a study published online Jan. 24 in Diabetes, Obesity and Metabolism.

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30-day Mortality Down With Vancomycin in C. difficile

TUESDAY, Feb. 7, 2017 (HealthDay News) -- For patients with Clostridium difficile infection (CDI), recurrence rates are similar with vancomycin and metronidazole treatment, but the risk of 30-day mortality is significantly reduced with vancomycin, according to a study published online Feb. 6 in JAMA Internal Medicine.

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CDC Issues Updated Immunization Schedule

TUESDAY, Feb. 7, 2017 (HealthDay News) -- A new adult vaccine schedule from the U.S. Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices has been published online Feb. 7 in the Annals of Internal Medicine.

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AAP: Improvement Needed in Adolescent Vaccination Rates

TUESDAY, Feb. 7, 2017 (HealthDay News) -- Adolescent rates of vaccination against human papillomavirus (HPV) and influenza are well below the target of 80 percent or higher, according to two American Academy of Pediatrics (AAP) reports published online Feb. 6 in Pediatrics.

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Fewer Toxic Chemicals Seen for E-Cigarette Use Versus Tobacco

TUESDAY, Feb. 7, 2017 (HealthDay News) -- Smokers who switch to electronic cigarettes can substantially reduce their intake of toxic chemicals and carcinogens -- but only if they completely quit smoking tobacco, according to a study published online Feb. 7 in the Annals of Internal Medicine.

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Lower Rate of Adverse Events With Outpatient Treatment of PE

MONDAY, Feb. 6, 2017 (HealthDay News) -- For patients with hemodynamically stable pulmonary embolism (PE), outpatient management is associated with a lower rate of adverse events, according to research published online Jan. 20 in the Journal of Thrombosis and Haemostasis.

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Variation in Prescribing Practices for Pediatric Atopic Dermatitis

MONDAY, Feb. 6, 2017 (HealthDay News) -- Prescribing practices vary among U.S. and Canadian physicians treating severe childhood atopic dermatitis (AD), according to a study published in the February issue of the Journal of the American Academy of Dermatology.

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Fewer Major Bleeds With Once- Versus Twice-Daily Enoxaparin

MONDAY, Feb. 6, 2017 (HealthDay News) -- Once-daily enoxaparin is associated with fewer major bleeds than enoxaparin twice daily in patients with acute venous thromboembolism (VTE), according to a study published online Jan. 25 in the Journal of Thrombosis and Haemostasis.

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Herb and Supplement Use Increasing in Pregnant Women

MONDAY, Feb. 6, 2017 (HealthDay News) -- From 2002 to 2012 there was an increase in herb and supplement use among pregnant women, according to a research letter published in the February issue of the American Journal of Obstetrics and Gynecology.

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Veterinary Pharmaceuticals Pose a Poisoning Risk to Children

MONDAY, Feb. 6, 2017 (HealthDay News) -- The flea medications and heartworm pills that millions of Americans give to their pets pose poisoning risks to any children in the home, according to research published online Feb. 6 in Pediatrics.

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CDC: HIV Still Undertreated in U.S. Black Population

FRIDAY, Feb. 3, 2017 (HealthDay News) -- Although progress has been made, blacks in America are still disproportionately affected by HIV/AIDS, according to research published in the Feb. 3 issue of the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report.

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NSAIDs Found to Be of Little Benefit to Patients With Back Pain

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Nonsteroidal anti-inflammatory drugs (NSAIDs) don't help most patients with back pain, according to a review published online Feb. 2 in the Annals of the Rheumatic Diseases.

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Underuse, Misuse of Hormone Tx in Breast Cancer Still Occurring

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Adjuvant endocrine therapy (AET) can reduce the likelihood that women diagnosed with certain breast cancers will experience a recurrence of their disease, but these treatments are still too seldom utilized, or used incorrectly, according to a study published online Feb. 2 in JAMA Oncology.

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Bicalutamide Improves Survival After Prostate Cancer Returns

THURSDAY, Feb. 2, 2017 (HealthDay News) -- When prostate cancer recurs after surgery, treatment with both radiation and bicalutamide can extend some men's lives, according to a study published in the Feb. 2 issue of New England Journal of Medicine.

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Patient Infected With HIV Despite Long-Term Adherence to PrEP

THURSDAY, Feb. 2, 2017 (HealthDay News) -- In a letter to the editor published in the Feb. 2 issue of the New England Journal of Medicine, authors present the case of a Canadian man infected with HIV despite long-term adherence to pre-exposure prophylaxis (PrEP).

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Surgery Can Benefit T2DM Control for Patients With Lumbar Stenosis

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Successful lumbar surgery is associated with improved glycemic control for patients with lumbar spinal stenosis (LSS) and type 2 diabetes mellitus (DM-2), according to a study published in the February issue of The Spine Journal.

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Lifetime Genistein Intake May Improve Response to Tamoxifen

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Lifetime intake of soy isoflavone genistein (GEN) improves the response of mammary tumors to tamoxifen (TAM) therapy in a rat model, according to an experimental study published online Feb. 1 in Clinical Cancer Research.

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Recommendations Updated for Diagnosis, Management of COPD

THURSDAY, Feb. 2, 2017 (HealthDay News) -- Recommendations have been updated for diagnosis, management, and prevention of chronic obstructive pulmonary disease (COPD), according to the Global Initiative for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease (GOLD) report published online Jan. 27 in the American Journal of Respiratory and Critical Care Medicine.

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Psychostimulants May Be Helpful in Treatment of Bulimia Nervosa

WEDNESDAY, Feb. 1, 2017 (HealthDay News) -- For select patients, psychostimulants may be beneficial for treating bulimia nervosa, according to a study of six cases published online Jan. 23 in the Journal of Clinical Pharmacology.

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Benefits for Intensive BP Lowering in Older HTN Patients

WEDNESDAY, Feb. 1, 2017 (HealthDay News) -- For older patients with hypertension, intensive blood pressure (BP) lowering strategies are associated with reduced risk of certain cardiovascular events, according to research published in the Feb. 7 issue of the Journal of the American College of Cardiology.

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HbA1c, Waist-to-Height Ratio Predict Dyslipidemia in T1DM

WEDNESDAY, Feb. 1, 2017 (HealthDay News) -- For youth with type 1 diabetes, hemoglobin A1c (A1C) and waist-to-height ratio (WHtR) are modifiable risk factors that predict change in dyslipidemia, according to a study published online Jan. 26 in Diabetes Care.

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