Musculoskeletal Symptoms Predict Psoriatic Arthritis

This article originally appeared here.
Share this content:
Musculoskeletal Symptoms Predict Psoriatic Arthritis
Musculoskeletal Symptoms Predict Psoriatic Arthritis

MONDAY, March 13, 2017 (HealthDay News) -- For patients with psoriasis, nonspecific musculoskeletal symptoms, including joint pain, fatigue, and stiffness, predict the development of psoriatic arthritis (PsA), according to a study published in the March issue of Arthritis & Rheumatology.

Lihi Eder, M.D., Ph.D., from the University of Toronto, and colleagues conducted a prospective cohort study involving patients with psoriasis who were assessed at baseline and reassessed annually to examine development of clinical PsA. At each visit, the presence of musculoskeletal symptoms and the patients' assessments of pain, fatigue, stiffness, physical function, and psychological distress were recorded.

The researchers found that 57 of 410 patients with psoriasis developed PsA. Prediction of subsequent PsA was associated with baseline presence of arthralgia in women (hazard ratio [HR], 2.59), heel pain (HR, 4.18), high fatigue score (HR, 2.36), and high stiffness score (HR, 2.03). Increases from baseline in fatigue, pain, and stiffness scores (HRs, 1.27, 1.34, and 1.21, respectively), and a worsening in physical function score (HR, 0.96) also predicted PsA development.

"A preclinical phase exists in patients with PsA prior to the diagnosis of the disease," the authors write. "This phase is characterized by nonspecific musculoskeletal symptoms, including joint pain, fatigue, and stiffness."

Abstract
Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

Risk for Interval CRC Higher in Blacks Than Whites

Risk for Interval CRC Higher in Blacks Than ...

Differences most pronounced for cancer of the distal colon and the rectum

Even Small Amounts of Alcohol Can Affect Breast Cancer Risk

Even Small Amounts of Alcohol Can Affect Breast ...

Small glass of wine each day can up odds of both premenopausal and postmenopausal breast cancer

ATS: Angiotensin II Improves BP in Vasodilatory Shock

ATS: Angiotensin II Improves BP in Vasodilatory Shock

Angiotensin II effective for vasodilatory shock in patients not responding to conventional vasopressors

is free, fast, and customized just for you!

Already a member?

Sign In Now »