Low Body Mass Index Not Risk Factor for Alzheimer's Disease

Share this content:
Low Body Mass Index Not Risk Factor for Alzheimer's Disease
Low Body Mass Index Not Risk Factor for Alzheimer's Disease

WEDNESDAY, May 10, 2017 (HealthDay News) -- There is no link between low body mass index (BMI) and risk of Alzheimer's disease, according to a study published online May 9 in the Journal of Clinical Endocrinology & Metabolism.

Researchers examined blood and DNA samples collected from 95,578 people in a major Danish population study. Of these people, 645 were diagnosed with Alzheimer's disease. The DNA of these patients was analyzed for signs of five gene types associated with BMI. The participants were then divided into one of four groups, based on their genetic likelihood for being overly thin.

The investigators found that gene variants tied to low BMI were not associated with an increased risk for Alzheimer's disease. The scientists did find a relationship between gene variants associated with having a high BMI and type 2 diabetes, but there was no such connection in terms of Alzheimer's.

"We found individuals with lifelong low BMI due to genetic variation were not at increased risk of Alzheimer's disease," senior author Ruth Frikke-Schmidt, M.D., Ph.D., an associate research professor at the University of Copenhagen in Denmark, said in a news release from the Endocrine Society. "The association can likely be explained by the fact that individuals with Alzheimer's disease are more likely to have low BMIs due to loss of appetite and weight loss in the early stages of the disease."

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

Trending Activities

All Professions

More in Home

SAMHSA: Youth Binge Drinking Rates Down in the United States

SAMHSA: Youth Binge Drinking Rates Down in the ...

But one in seven still consumed excess alcohol at least once in past month, study finds

Carpal Tunnel Up With Increased Electronic Device Use

Carpal Tunnel Up With Increased Electronic Device Use

Especially for those who spend more than five hours a day on their devices, researchers say

Guided Approach to Exercise May Help Chronic Fatigue Patients

Guided Approach to Exercise May Help Chronic Fatigue ...

Guided self-help approach to graded exercise program safe, reduces fatigue

is free, fast, and customized just for you!

Already a member?

Sign In Now »