Biomarker in Nasal Passages May ID Lung Cancer in Smokers

Share this content:
Biomarker in Nasal Passages May ID Lung Cancer in Smokers
Biomarker in Nasal Passages May ID Lung Cancer in Smokers

TUESDAY, Feb. 28, 2017 (HealthDay News) -- DNA-based biomarkers in the nasal passages may be able to reveal whether a lung lesion is cancerous or not, according to a study published online Feb. 27 in the Journal of the National Cancer Institute.

The new study involved patients -- current or former smokers -- undergoing diagnostic evaluation for pulmonary lesions suspicious for lung cancer. The participants were enrolled at 28 medical centers in North America and Europe. The researchers took nasal swabs from the patients.

The team identified a pattern of 30 genes that were differentially expressed in patients confirmed to have lung cancer.

"These results support that the airway epithelial field of lung cancer-associated injury in ever smokers extends to the nose and demonstrates the potential of using nasal gene expression as a noninvasive biomarker for lung cancer detection," the authors write.

Two authors disclosed receiving fees from medical companies, and one author disclosed related patents.

Abstract/Full Text (subscription or payment may be required)

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

ATS: Cancer-Related Suicide Risk Highest for Lung Cancer Patients

ATS: Cancer-Related Suicide Risk Highest for Lung Cancer ...

Odds up four-fold compared to people in the general population

Mortality Rates Found Lower at Major Teaching Hospitals

Mortality Rates Found Lower at Major Teaching Hospitals

Researchers assessed 30-day survival for older patients

Opioid Use Before TKA May Lead to Worse Pain After Surgery

Opioid Use Before TKA May Lead to Worse ...

Researchers suggest limiting opioid prescriptions might optimize benefits of TKA

is free, fast, and customized just for you!

Already a member?

Sign In Now »