Nifedipine Not Superior to Placebo for Chronic Chilblains

This article originally appeared here.
Share this content:
Nifedipine Not Superior to Placebo for Chronic Chilblains
Nifedipine Not Superior to Placebo for Chronic Chilblains

FRIDAY, Sept. 16, 2016 (HealthDay News) -- For patients with chronic chilblains, nifedipine is not superior to placebo, according to a study published in the September/October issue of the Annals of Family Medicine.

Ibo H. Souwer, M.D., from the Radboud University Medical Center in the Netherlands, and colleagues conducted a randomized trial involving 32 patients with chronic chilblains. Participants were randomized to nifedipine (30 mg controlled release twice daily) or placebo.

After six weeks of treatment, the researchers found that in mean scores on the visual analogue scale on complaints, there was a nonsignificant difference of 1.84 mm in favor of nifedipine. There was a nonsignificant difference of 0.56 mm in favor of placebo in mean scores on the visual analogue scale on disability. No carry-over effect was seen from prior study treatment. There was a correlation for nifedipine with significantly lower systolic blood pressure and a significantly higher incidence of edema.

"In our study, nifedipine was not superior to placebo for treating chronic chilblains," the authors write. "These findings contrast with those of the older study and do not support routine use of nifedipine for this condition."

Abstract
Full Text

Share this content:

is free, fast, and customized just for you!

Already a member?

Sign In Now »


Sign up for myCME e-newsletters


Drug Lookup

Browse drugs by: BrandGenericDisease

More in Home

FDA Approves Keytruda for All Cancers With Genetic Biomarker

FDA Approves Keytruda for All Cancers With Genetic ...

First medication sanctioned for any cancer, regardless of origin

Regular Chocolate Consumption May Lower Risk of A-Fib

Regular Chocolate Consumption May Lower Risk of A-Fib

13-year study finds lower odds for atrial fibrillation in people eating moderate amounts

Doctors Urged to Check Patient Drug History Before Opioid Rx

Doctors Urged to Check Patient Drug History Before ...

Opioid abuse down when physicians are legally obligated to check patient's drug history

is free, fast, and customized just for you!

Already a member?

Sign In Now »