This activity is provided by Paradigm Medical Communications, LLC.
In collaboration with the Hospital Quality Foundation.
This activity is supported by an educational grant from Novartis Pharmaceuticals Corporation.
This activity covers the underlying pathophysiology of chronic heart failure to help clinicians differentiate heart failure with reduced ejection fraction and heart failure with preserved ejection fraction. The 2013 ACCF/AHA Guideline for the Management of Heart Failure is reviewed as it relates to pharmacotherapy recommendations, including conventional drug classes such as ACEI/ARBs, beta blockers, diuretics, and aldosterone antagonists. Expert guidance is provided on: the role of new and emerging agents with novel mechanisms of action; the safety and efficacy data from their related clinical trials; and the potential role of these agents in clinical practice.
Table of Contents
Chapter 1: Introduction to Chronic Heart Failure Chapter 2: Pathophysiology of Chronic Heart Failure Chapter 3: Guideline Recommendations for Management of Chronic Heart Failure Chapter 4: Recently Approved Agents for Management of Chronic Heart Failure Chapter 5: Tying it All Together Additional Resources For Healthcare Practitioners References
This activity has been designed to address the educational needs of physicians specializing in cardiology, interventional cardiology, heart failure, internal medicine, hospital medicine, pulmonary medicine, emergency medicine, and primary care. This activity will also be of benefit to nurse practitioners, PAs, and other clinicians interested in the management of chronic heart failure.
Upon proper completion of this activity, participants should be better able to:
Describe the underlying pathophysiology of chronic heart failure, including differentiation between heart failure with reduced or preserved left ventricular ejection fraction
Review the 2013 ACCF/AHA heart failure guidelines and the basis for the recommendations along with the 2016 ACC/AHA/HFSA update to the guidelines
Describe the background information supporting the 2016 guideline update including mechanisms of action, clinical evidence for, and appropriate use of newer heart failure therapies
Conflict Of Interest Disclosure Policy
In accordance with Accreditation Council for Continuing Medical Education requirements on disclosure, faculty and contributors are asked to disclose any relationships with commercial interests associated with the area of medicine featured in the activity. These relationships are described below.
Resolution of Conflict of Interest
Paradigm Medical Communications, LLC, has implemented a system to resolve conflicts of interest for each CME activity to help ensure content is objective, independent, fairly balanced, and aligned with the public interest. Conflicts, if any, are resolved through one or more processes. All CME content in this activity has been independently reviewed to ensure that it is free of commercial bias, scientifically rigorous, aligned with the public interest, and compliant with all regulatory guidance and the ACCME’s Standards for Commercial Support of Continuing Medical Education.
JoAnn Lindenfeld, MD (Chair) Professor of Medicine Director, Heart Failure and Transplant Section Vanderbilt University Nashville, TN
Dr. Lindenfeld discloses the following: Retained Consultant: Abbott, CVRx, Edwards Lifesciences Corporation, Novartis, Relypsa Inc., ResMed, V-Wave Ltd.
Mark E. Dunlap, MD Professor of Medicine, Physiology, and Biophysics Case Western Reserve University Director, Heart Failure Section Heart and Vascular Center The MetroHealth System Cleveland, OH
Dr. Dunlap has no financial relationships to disclose.
Herb Patterson, PharmD Professor of Pharmacy Research Professor of Medicine Eshelman School of Pharmacy University of North Carolina Chapel Hill, NC
Dr. Patterson discloses the following: Grant/Research Support: Novartis; Otsuka America Pharmaceutical, Inc. Retained Consultant: Amgen Inc.; Novartis
Accredited Provider Disclosure
Paradigm Medical Communications, LLC staff members have no financial relationships to disclose.
Independent peer reviewer has no financial relationships to disclose.
AMA PRA Category 1 Credit(s)TM
Paradigm Medical Communications, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
Paradigm Medical Communications, LLC designates this enduring material for a maximum of 1.00 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Additional Credit Information
PA Continuing Education AAPA accepts certificates of participation for educational activities certified for AMA PRA Category 1 CreditTM from organizations accredited by ACCME or a recognized state medical society. PAs may receive a maximum of 1.00 Category 1 credit for completing this activity.
Nurse Practitioner Continuing Education The American Academy of Nurse Practitioners Certification Program (AANPCP) accepts certificates of participation for educational activities certified for AMA PRA Category 1 CreditTM from organizations accredited by the ACCME. Individuals are responsible for checking with the AANPCP for further guidelines.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.
This CME activity represents the views and opinions of the individual faculty, and does not constitute the opinion or endorsement of, or promotion by, Paradigm Medical Communications, LLC. Reasonable efforts have been taken to present educational subject matter in a balanced, unbiased fashion, and in compliance with regulatory requirements. However, each activity participant must always use his or her own personal and professional judgment when considering further application of this information, particularly as it may relate to patient diagnostic or treatment decisions including, without limitation, FDA-approved uses and any off-label uses.
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To receive a CME certificate of participation, you should:
Follow the "Start Activity" button to go to the Paradigm Medical Communications website, where you will complete the pretest.
View the online activity in its entirety.
Complete and submit the online post-test and evaluation. You must answer 70% of the post-test questions correctly to earn credit. You will have unlimited opportunities to successfully complete the post-test.
A certificate of participation will be available for download/printing immediately following your successful completion of the post-test and evaluation. Your certificate will be saved on the Paradigm Medical Communications website and will not be available in your myCME CME History.
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Disclaimer The materials provided for this activity are for informational purposes only, and should not be used for diagnosis or treatment of a health problem without consulting a licensed medical professional. Any views or opinions presented are solely those of the faculty, and do not necessarily represent those of Paradigm Medical Communications, LLC. References to any entity, product, service, or source of information on this website should not be considered an endorsement, either direct or implied, by Paradigm Medical Communications, LLC. Paradigm Medical Communications, LLC accepts no liability for the content referenced in this activity.
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Paradigm Medical Communications, LLC does not transfer, sell, or share personal information with outside parties. Paradigm Medical Communications, LLC will not otherwise disclose personal information unless required to in a legal process. Paradigm Medical Communications, LLC staff members review individual test results to the extent necessary to record and track participants’ credits.